Croscarmellose Sodium (CCS)
Introduction:
Croscarmellose Sodium (CCS) is a superdisintegrant used in pharmaceutical solid dosage formulations to aid in the rapid disintegration and dissolution of tablets and capsules. It is produced from high-quality, non-GMO wood pulp and contains no starch or sugars, ensuring high purity and effectiveness even at low dosages.
Key Features:
Superior disintegration and dissolution properties
Very fine particle size for enhanced functionality
Ethanol used as a safe solvent in the production process
Kosher and Halal certified
Compliant with US DMF and ICH Q3D elemental impurities guidelines
Applications:
Pharmaceuticals
Disintegrant in tablets, capsules, and oral formulations.
Cosmetics
Used as a thickener and stabilizer in creams and lotions.
Packaging:
Available in 25 kg and 50 kg Paper Bags, HDPE Bags, or Fiber Drums.
Available Brands and Grades Comparative Characteristics:
| Grade | GMO-free | Loss on Trying | Solved Content | Regulatory | |
|---|---|---|---|---|---|
| CELLOSOL® GF | Yes | NMT 10% | NMT 0.5% EtOH | Ph. Eur., NF, JP | A cellulose-based superdisintegrant, providing excellent results in tablet disintegration. Used at a level of 1-4 % only, it is one of the most efficient superdisintegrants in the pharmaceutical technology, which can be used in all tableting processes. Especially recommended for medium soluble actives. |
| CELLOSOL® GF LM | Yes | NMT 6% | NMT 0.03 % EtOH | Suitable for food applications (E468) | |
| CELLOSOL CLP | No | NMT 6 % | NMT 0.03% EtOH | BP, IP |